Verastem Inc. (NASDAQ: VSTM) is a clinical stage biopharmaceutical company focused on discovering and developing drugs to improve outcomes for patients with cancer. Verastem's product candidates seek to treat cancer by targeting malignant cells both directly and through modulation of the tumor microenvironment. Our most advanced programs target the phosphoinositide-3-kinase (PI3K) and Focal Adhesion Kinase (FAK) pathways.
Major advances in cancer treatment have led to significant improvements in efficacy. However, this benefit does not extend to all patients. Challenges in the tumor microenvironment may both support tumor survival, and inhibit anti-tumor activity of cancer therapies and adaptive immune response.