Research

Publications

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Verastem ResourcesMerlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship
Shapiro IM, Kolev VN, Vidal CM, Kadariya Y, Ring JE, Wright Q, Weaver DT, Menges C, Padval M, McClatchey AI, Xu Q, Testa JR, Pachter JA.
May 21, 2014
Vol. 6, Issue 237, p. 237ra68 Science Transitional Medicine DOI: 10.1126/scitranslmed.3008639

Verastem ResourcesVS-5584, a Novel and Highly Selective PI3K/mTOR Kinase Inhibitor for the Treatment of Cancer
Hart S, Novotny-Diermayr V, Goh KC, Williams M, Tan YC, Ong LC, Cheong A, Ng BK, Amalini C, Madan B, Nagaraj H, Jayaraman R, Pasha KM, Ethirajulu K, Chng WJ, Mustafa N, Goh BC, Benes C, McDermott U, Garnett M, Dymock B, and Wood JW.
February 18, 2013
Molecular Cancer Therapeutics: Mol Cancer Ther; 12(2); 151–61. ©2012 AACR.

Verastem ResourcesThe outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions.
Shibue T, Brooks MW, Inan MF, Reinhardt F, Weinberg RA.
August 02, 2012
Cancer Discov. 2012 Aug;2(8):706-21

Verastem ResourcesStochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
Piyush B. Gupta, Christine M. Fillmore, Guozhi Jiang, Sagi D. Shapira, Kai Tao, Charlotte Kuperwasser, Eric S. Lander
July 26, 2011
Cell, Volume 146, Issue 4, 633-644

Verastem ResourcesHallmarks of Cancer: The Next Generation
Douglas Hanahan, Robert A. Weinberg
March 04, 2011
Cell, Volume 144, Issue 5, 646-674

Verastem ResourcesCancer Stem Cells: Mirage or Reality?
Gupta PB, Chaffer CL, Weinberg RA.
September 15, 2009
Nat Med. 2009 Sep;15(9):1010-2.

Verastem ResourcesIdentification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES
August 13, 2009
Cell. 2009 Aug 21;138(4):645-59

Verastem ResourcesThe Epithelial-Mesenchymal Transition Generates Cells With Properties of Stem Cells.
Sendurai A. Mani, Wenjun Guo, Mai-Jing Liao, Elinor Ng. Eaton, Ayyakkannu Ayyanan, Alicia Y. Zhou, Mary Brooks, Ferenc Reinhard, Cheng Cheng Zhang, Michail Shipitsin, Lauren L. Campbell, Kornelia Polyak, Cathrin Brisken, Jing Yang, and Robert A. Weinberg.
May 08, 2008
Cell, Volume 133, Issue 4, 704-715